2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W012550R
    D-Carnitine (Standard)
    		Inhibitor
    D-Carnitine (Standard) is the analytical standard of D-Carnitine. This product is intended for research and analytical applications. D-Carnitine is an orally available isomer of the essential nutrient L-carnitine that promotes long-chain fatty acid transport into the mitochondrial matrix for beta-oxidation. D-Carnitine has antiparasitic activity.
    D-Carnitine (Standard)
  • HY-W768856
    Artemether-13C,d3
    Artemether-13C,d3 (Dihydroqinghaosu methyl ether-13C,d3) is the deuterium and 13C-labeled Artemether (HY-N0402). Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria.
    Artemether-<sup>13</sup>C,d<sub>3</sub>
  • HY-159637
    IWY357
    		Inhibitor
    IWY357 is a long-acting, blood-stage inhibitor of Plasmodium falciparum.
    IWY357
  • HY-100593A
    Spiramycin (hexanedioate)
    		Inhibitor
    Spiramycin hexanedioate (Rovamycin) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect. Spiramycin hexanedioate is composed of a 16-member lactone ring, on which three sugars (mycaminose, forosamine, and mycarose) are attached.
    Spiramycin (hexanedioate)
  • HY-125134
    Alloaromadendrene
    Alloaromadendrene, an antioxidant, can be isolated from the leaves of mixed-type C. osmophloeum. Alloaromadendrene protects C. elegans against oxidative stress induced by walnut quinone and prolongs the life of C. elegans.
    Alloaromadendrene
  • HY-168262
    Antitrypanosomal agent 22
    		Inhibitor
    Antitrypanosomal agent 22 (compound 13) is a nitrothienylazine compound with trypanosomaticidal efficacy. Antitrypanosomal agent 22 shows leishmanicidal and trypanocidal with in vitro submicromolar activities, and devoid of toxicity on mammalian cells are uncovered.
    Antitrypanosomal agent 22
  • HY-P5344
    Dabcyl-LNKRLLHETQ-Edans
    		Inhibitor
    Dabcyl-LNKRLLHETQ-Edans (Fluorigenic PEXEL peptide) is a biological active peptide. (This FRET substrate peptide for Plasmepsin V (PMV) is derived from the conserved Plasmodium Export Element (PEXEL) motif of Histidine-Rich Protein II (HRPII). PMV is an ER aspartic protease that recognizes and cleaves the RXL sequence within the PEXEL motif of proteins exported by human malaria parasite Plasmodium falciparum, allowing them to translocate into host erythrocytes.)
    Dabcyl-LNKRLLHETQ-Edans
  • HY-120104
    Nitidanin
    		Inhibitor
    Nitidanin ((±)-Nitidanin) is an antimalarial and antiviral compound that can be isolated from the wood of Xanthoxylum nitidun D. C. Nitidanin is shows IC50 values of 21.2 and 18.4 μM for D6 and W2 clones of Plasmodium falciparum, respectively. Nitidanin can be used for the research of malaria and virus infection.
    Nitidanin
  • HY-B2031S
    Pyriproxyfen-d6
    Pyriproxyfen-d6 is the deuterium labeled Pyriproxyfen.
    Pyriproxyfen-d<sub>6</sub>
  • HY-N12146
    Spinosyn D 17-pseudoaglycone
    		Inhibitor
    Spinosyn D 17-pseudoaglycone is a hydrolysis product of the minor insecticide component Spinosyn D (HY-125326).
    Spinosyn D 17-pseudoaglycone
  • HY-147857
    Antileishmanial agent-12
    		Inhibitor
    Antileishmanial agent-12 (compound 5a) is a potent anti-leishmanial agent. Antileishmanial agent-12 shows antiprotozoal activity against Leishmania brazilensis, Leishmania infantum, and T. cruzi, with IC50 values of 14.9, 21.3 and 9.3 μM, respectively.
    Antileishmanial agent-12
  • HY-N2230R
    N-p-trans-Coumaroyltyramine (Standard)
    		Inhibitor
    N-p-trans-Coumaroyltyramine (Standard) is the analytical standard of N-p-trans-Coumaroyltyramine (HY-N2230). This product is intended for research and analytical applications. N-p-trans-Coumaroyltyramine is a natural phenolic amide compound and an inhibitor of AChE (IC50: 122 μM) and α-glucosidase (IC50: 2.7 μM). N-p-trans-Coumaroyltyramine also has anti-trypanosomal activity, with an IC50 of 13.3 µM against T. brucei rhodesiense. N-p-trans-Coumaroyltyramine can be used in the research of diseases such as Alzheimer's disease.
    N-p-trans-Coumaroyltyramine (Standard)
  • HY-118427
    Asterriquinol D dimethyl ether
    		Inhibitor
    Asterriquinol D dimethyl ether is a fungal metabolite, which can inhibit mouse myeloma NS-1 cell lines with an IC50 of 28 μg/mL. Asterriquinol D dimethyl ether also inhibits Tritrichomonas foetus.
    Asterriquinol D dimethyl ether
  • HY-N1944S
    Nerolidol-d4
    		Inhibitor
    Nerolidol-d4 is deuterated labeled Nerolidol (HY-N1944). Nerolidol has multiple natural membrane activities, possesses anti-cancer, anti-inflammatory, antibacterial and anti-insect activity. Nerolidol Suppresses parasitic activity, suppresses bloodsucking diseases, bloodworm diseases, and other diseases. Nerolidol can protect the cells from lipid and protein properties, damage to DNA, and protect the cells from damage.
    Nerolidol-d<sub>4</sub>
  • HY-151433
    Antiparasitic agent-10
    		Inhibitor
    Antiparasitic agent-10 (Compound 94) is an anti-parasitic agent, shows anti-schistosomal activity. Antiparasitic agent-10 shows activity against adults of Schistosoma mansoni, and can be used in Schistosomiasis research.
    Antiparasitic agent-10
  • HY-10373B
    Trimetrexate isethionate
    		Inhibitor
    Trimetrexate (CI-898) isethionate is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate isethionate can also inhibit the growth of various cancer cells. Trimetrexate isethionate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer.
    Trimetrexate isethionate
  • HY-170431
    SAL-0010042
    		Inhibitor
    SAL-0010042 is the inhibitor for Plasmodium phosphodiesterase β (PDEβ), that inhibits the hydrolysis of cAMP and cGMP (IC50=48.9 nM) in gametocytes, activates PKG, and inhibits the growth and development of Plasmodium (IC50 for 3D7 and Dd2 is 142 nM and 218 nM). SAL-0010042 inhibits hPDE5 and hPDE6 with IC50 of 632 nM and 73 nM.
    SAL-0010042
  • HY-W159102
    8CN
    		Inhibitor
    8CN, a 2-amino-thiophene derivative, has anti-leishmanial activity. 8CN can be used in research of Leishmaniasis.
    8CN
  • HY-N10697
    Angulatin G
    		Inhibitor
    Angulatin G (Celangulatin E) is an insecticidal sesquiterpene polyol ester with a β-dihydroagarofuran sesquiterpene skeleton, which can be isolated from the root bark of Celastrus angulatus. Angulatin G shows LD50 against Mythimna separata of 1656.4 μg/mL.
    Angulatin G
  • HY-149782
    Phosphodiesterase-IN-1
    		Inhibitor
    Phosphodiesterase-IN-1 (Compound 7) is a phosphodiesterase (PDE) inhibitor with anti-Plasmodium activity. Phosphodiesterase-IN-1 has antiproliferative activity against P. falciparum (strain 3D7) with an IC50 value of 0.64 μM.
    Phosphodiesterase-IN-1
Parasite Isoform Comparison

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